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Immunogen sequence: QDRTLHVRYT DIDYQVFTDA ARFVTEGRSP YLRATYRYT
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
PIGM encodes a transmembrane protein that is located in the endoplasmic reticulum and is involved in GPI-anchor biosynthesis. The glycosylphosphatidylinositol (GPI)-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. PIGM encodes a mannosyltransferase, GPI-MT-I, that transfers the first mannose to GPI on the lumenal side of the endoplasmic reticulum.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: dol-P-Man dependent GPI mannosyltransferase; DPM:GlcN-(acyl-)PI mannosyltransferase; GPI mannosyltransferase 1; GPI mannosyltransferase I; GPI-MT-I; phosphatidylinositol glycan anchor biosynthesis, class M; Phosphatidylinositol-glycan biosynthesis class M protein; PIG-M; PIG-M mannosyltransferase
Gene Aliases: GPI-MT-I; PIGM
UniProt ID: (Human) Q9H3S5
Entrez Gene ID: (Human) 93183
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