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Proteintech
PIK3C2G Polyclonal Antibody
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Product Details
25904-1-AP
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PIK3C2G Fusion Protein Ag23177 (11-336 aa encoded by BC130277)
Conjugate
Form
Liquid
Concentration
0.39 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: PNESHEKQY EHQEFLFVNQ PHSSSQVSLG FDQIVDEISG KIPHYESEID ENTFFVPTAP KWDSTGHSLN EAHQISLNEF TSKSRELSWH QVSKAPAIGF SPSVLPKPQN TNKECSWGSI GKHHGADDSR FSILALSFTS LDKINLEKEL ENENHNYHIG FESSIPPTNS SFSSDFMPKE ENKRSGHVNI VEPSLMLLKG SLQPGMWEST WQKNIESIGC SIQLVEVPQS SNTSLASFCN KVKKIRERYH AADVNFNSGK IWSTTTAFPY QLFSKTKFNI HIFIDNSTQP LHFMPCANYL VKDLIAEILH FCTNDQLLPK DHILSVC (11-336 aa encoded by BC130277)
Target Information
PIK3C2G lipid kinase belongs to the phosphoinositide 3-kinase (PI3K) family which play major roles in signaling pathways and are involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. PIK3C2G contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases that act as calcium-dependent phospholipid binding motifs which mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The N-terminal region of PIK3C2G and the C-terminal C2 domain are required for enzymatic activity. The PI 3-kinase C2gamma gene encodes a 1,050 amino acid polypeptide with 36% identity to human PI 3-kinase C2alpha. Research indicates that PI 3-kinase C2gamma can block the growth of human colon cancer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing gamma polypeptide; phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit gamma; Phosphoinositide 3-kinase-C2-gamma; phosphoinositide-3-kinase, class 2, gamma polypeptide; PI 3-kinase C2gamma; PI3K-C2-gamma; PI3KC2gamma; PTDINS-3-kinase C2 gamma
Gene Aliases: PI3K-C2-gamma; PI3K-C2GAMMA; PIK3C2G
UniProt ID: (Human) O75747
Entrez Gene ID: (Human) 5288
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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