Invitrogen

PIK3R2 Recombinant Rabbit Monoclonal Antibody (6E2F5)

View all (21) PIK3R2 antibodies

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

MA5-42863

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:1,000
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

6E2F5

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 100-200 of human PI3 Kinase p85 beta (O00459).
View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 0.05% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2912004

Product Specific Information

Positive test controls include: MCF7, K-562, Rat brain.

Immunogen sequence: PRDGAPEPGL TLPDLPEQFS PPDVAPPLLV KLVEAIERTG LDSESHYRPE LPAPRTDWSL SDVDQWDTAA LADGIKSFLL ALPAPLVTPE ASAEARRALR E

Target Information

Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; phosphatidylinositol 3-kinase regulartory subunit polypeptide 2; Phosphatidylinositol 3-kinase regulatory subunit beta; phosphatidylinositol 3-kinase, regulartory subunit, polypeptide 2; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta); phosphoinositide-3-kinase regulatory subunit beta; phosphoinositide-3-kinase, regulatory subunit 2 (beta); PI3-kinase p85 subunit beta; PI3-kinase regulatory subunit beta; PI3-kinase subunit p85-beta; PI3K; PI3K regulatory subunit beta; ptdIns-3-kinase p85-beta; ptdIns-3-kinase regulatory subunit beta; ptdIns-3-kinase regulatory subunit p85-beta

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Gene Aliases: MPPH; MPPH1; p85; p85-BETA; P85B; p85beta; PIK3R2

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UniProt ID: (Human) O00459, (Mouse) O08908

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Entrez Gene ID: (Human) 5296, (Mouse) 18709, (Rat) 29741

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Function(s)
GTPase activator activity protein binding 1-phosphatidylinositol-3-kinase activity protein phosphatase binding receptor tyrosine kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity 1-phosphatidylinositol-3-kinase regulator activity protein heterodimerization activity transcription factor binding phosphatidylinositol 3-kinase regulator activity phosphatidylinositol 3-kinase regulatory subunit binding
Process(es)
cellular glucose homeostasis phosphatidylinositol biosynthetic process insulin receptor signaling pathway regulation of autophagy phosphatidylinositol 3-kinase signaling regulation of phosphatidylinositol 3-kinase signaling protein transport cellular response to insulin stimulus response to endoplasmic reticulum stress phosphatidylinositol-3-phosphate biosynthetic process Fc-epsilon receptor signaling pathway Fc-gamma receptor signaling pathway involved in phagocytosis positive regulation of transcription factor import into nucleus positive regulation of GTPase activity regulation of phosphatidylinositol 3-kinase activity positive regulation of transcription from RNA polymerase II promoter phosphatidylinositol phosphorylation vascular endothelial growth factor receptor signaling pathway phosphatidylinositol-mediated signaling T cell receptor signaling pathway leukocyte migration regulation of small GTPase mediated signal transduction positive regulation of glucose import in response to insulin stimulus transport signal transduction regulation of actin filament polymerization regulation of phosphorylation positive regulation of cell adhesion regulation of stress fiber assembly regulation of establishment of protein localization to plasma membrane phosphorylation
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