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          • Primary Antibodies ›
          • PKC delta/theta Antibodies

          Invitrogen

          PKC delta/theta Recombinant Rabbit Monoclonal Antibody (23GB4585)

          Advanced Verification
          View all (3) PKC delta/theta antibodies

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          Datasheet
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          Datasheet
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          Cite PKC delta/theta Recombinant Rabbit Monoclonal Antibody (23GB4585)

          • Antibody Testing Data (3)
          • Advanced Verification (1)
          PKC delta/theta Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          PKC delta/theta Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          PKC delta/theta Antibody (MA5-53774) in ICC/IF

          Immunocytochemistry analysis of PKC delta/theta in HT-1080 cells. Nuclei were stained blue with DAPI; PKC delta/theta recombinant monoclonal antibody (Product # MA5-53774) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
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          PKC delta/theta Antibody in Immunocytochemistry (ICC/IF)
          PKC delta/theta Antibody in Western Blot (WB)
          PKC delta/theta Antibody in Flow Cytometry (Flow)
          PKC delta/theta Antibody

          Product Details

          MA5-53774

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:5,000
          -

          Immunocytochemistry (ICC/IF)

          1:1,000
          -

          Flow Cytometry (Flow)

          1:2,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Expression System

          HEK293F

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          23GB4585

          Immunogen

          A synthesized peptide derived from human PKC delta+PKC theta (100-350AA).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_3248245

          Target Information

          PRKCD (Protein Kinase C Delta) is a Protein Coding gene. Diseases associated with PRKCD includeAutoimmune Lymphoproliferative Syndrome, Type IiiandSystemic Lupus Erythematosus 16. Among its related pathways areRole of Calcineurin dependent NFAT signaling in lymphocytesandWnt Signaling Pathway and Pluripotency. Gene Ontology (GO) annotations related to this gene includetransferase activity, transferring phosphorus containing groupsandprotein tyrosine kinase activity. An important paralog of this gene isPRKCQ (PKC theta).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: nPKC-delta; nPKC-theta; PKC theta; Protein kinase C delta type; protein kinase C delta variant IX; protein kinase C delta VIII; Protein kinase C theta type; protein kinase C, delta; protein kinase C, delta IV; protein kinase C, delta V; protein kinase C, theta; protein kinase C[d]; SDK-1; Tyrosine-protein kinase PRKCD

          View more View less

          Gene Aliases: A130035A12Rik; AI385711; ALPS3; AW494342; CVID9; D14Ertd420e; MAY1; nPKC-delta; nPKC-theta; PKC-0; PKC-theta; PKC[d]; PKCD; PKCdelta; Pkcq; PKCtheta; PRKCD; PRKCQ; PRKCT

          View more View less

          UniProt ID: (Human) Q05655, (Human) Q04759, (Mouse) P28867, (Rat) P09215, (Mouse) Q02111

          View more View less

          Entrez Gene ID: (Human) 5580, (Human) 5588, (Mouse) 18753, (Rat) 170538, (Mouse) 18761, (Rat) 85420

          View more View less

          Function(s)
          protein kinase activity protein serine/threonine kinase activity protein kinase C activity calcium-independent protein kinase C activity non-membrane spanning protein tyrosine kinase activity protein binding ATP binding enzyme activator activity enzyme binding kinase binding protein kinase binding insulin receptor substrate binding metal ion binding nucleotide binding kinase activity transferase activity transferase activity, transferring phosphorus-containing groups TIR domain binding
          Process(es)
          stimulatory C-type lectin receptor signaling pathway protein phosphorylation apoptotic process cellular component disassembly involved in execution phase of apoptosis cell cycle signal transduction activation of phospholipase C activity intrinsic apoptotic signaling pathway in response to oxidative stress regulation of receptor activity immunoglobulin mediated immune response histone phosphorylation peptidyl-serine phosphorylation peptidyl-threonine phosphorylation peptidyl-tyrosine phosphorylation termination of signal transduction platelet activation negative regulation of actin filament polymerization positive regulation of endodeoxyribonuclease activity negative regulation of protein binding activation of protein kinase activity interleukin-10 production interleukin-12 production positive regulation of superoxide anion generation regulation of actin cytoskeleton organization negative regulation of glial cell apoptotic process positive regulation of protein dephosphorylation Fc-gamma receptor signaling pathway involved in phagocytosis B cell proliferation neutrophil activation positive regulation of protein import into nucleus defense response to bacterium negative regulation of MAP kinase activity regulation of mRNA stability negative regulation of insulin receptor signaling pathway negative regulation of inflammatory response negative regulation of peptidyl-tyrosine phosphorylation protein stabilization negative regulation of filopodium assembly cell chemotaxis interferon-gamma-mediated signaling pathway cellular response to hydrogen peroxide cellular response to hydroperoxide negative regulation of platelet aggregation cellular senescence positive regulation of phospholipid scramblase activity cellular response to angiotensin positive regulation of ceramide biosynthetic process positive regulation of glucosylceramide catabolic process positive regulation of sphingomyelin catabolic process positive regulation of response to DNA damage stimulus positive regulation of apoptotic signaling pathway response to oxidative stress aspartate transport phosphorylation collagen metabolic process cellular response to oxidative stress intracellular signal transduction regulation of phosphorylation positive regulation of apoptotic process positive regulation of MAP kinase activity positive regulation of MAPK cascade positive regulation of glucose import protein autophosphorylation response to hypoxia aging response to heat response to mechanical stimulus response to glucose response to organonitrogen compound response to organic cyclic compound cellular response to insulin stimulus cellular response to glucose starvation response to drug response to hydrogen peroxide positive regulation of catalytic activity response to amino acid response to ethanol regulation of cell growth regulation of transcription, DNA-templated membrane protein ectodomain proteolysis inflammatory response axon guidance regulation of G2/M transition of mitotic cell cycle regulation of vasoconstriction positive regulation of telomere maintenance via telomerase positive regulation of interleukin-17 production positive regulation of interleukin-4 production response to insulin Fc-epsilon receptor signaling pathway positive regulation of T cell proliferation tissue regeneration positive regulation of NF-kappaB import into nucleus positive regulation of interleukin-2 biosynthetic process respiratory burst positive regulation of protein secretion T cell receptor signaling pathway positive regulation of T cell activation positive regulation of NF-kappaB transcription factor activity positive regulation of filopodium assembly positive regulation of stress fiber assembly positive regulation of telomerase activity negative regulation of T cell apoptotic process regulation of platelet aggregation positive regulation of telomere capping positive regulation of T-helper 17 type immune response positive regulation of T-helper 2 cell activation immune system process neuron differentiation
          It has to be done as per old AB suggested Products section.
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