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Abnova
PKD2L1 Monoclonal Antibody (4F9)
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Product Details
H00009033-M01
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
4F9
Immunogen
PKD2L1 (NP_057196.2, 173 a.a. approximately 272 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Tissue lysate).
Immunogen sequence: KWYNNQSLGH GSHSFIYYEN MLLGVPRLRQ LKVRNDSCVV HEDFREDILS CYDVYSPDKE EQLPFGPFNG TAWTYHSQDE LGGFSHWGRL TSYSGGGYYL
Target Information
This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. This protein functions as a calcium-regulated nonselective cation channel. Alternative splice variants have been described but their full length sequences have not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: PK2L1; Polycystic kidney disease 2-like 1 protein; Polycystin-2 homolog; Polycystin-2-like protein 1; Polycystin-2L1; Polycystin-L; Polycystin-L1; transient receptor potential cation channel, subfamily P, member 3
Gene Aliases: PCL; PKD2L; PKD2L1; PKDL; TRPP3
UniProt ID: (Human) Q9P0L9
Entrez Gene ID: (Human) 9033, (Rat) 293937
calcium activated cation channel activity
cation channel activity
calcium channel activity
sodium channel activity
calcium ion binding
protein binding
cytoskeletal protein binding
cation transmembrane transporter activity
calcium-activated potassium channel activity
sour taste receptor activity
identical protein binding
muscle alpha-actinin binding
alpha-actinin binding
detection of chemical stimulus involved in sensory perception of sour taste
cation transport
smoothened signaling pathway
sodium ion transmembrane transport
sensory perception of sour taste
detection of mechanical stimulus
protein homotrimerization
calcium ion transmembrane transport
cellular response to acidic pH
potassium ion transmembrane transport
cation transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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