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Immunogen sequence: QPVYEEPSDE VEAMTYLCRK LRTMFSFLTS QSKAKDEPEF FIDMLYGQPE KNSHRYLGLK TRNINGKKMV YL
Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 71%.
This intronless gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a receptor for egg jelly (REJ) domain, a G-protein-coupled receptor proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may play a role in human reproduction. Alternative splice variants have been described but their biological natures have not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PKD and REJ homolog; polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin); Polycystic kidney disease and receptor for egg jelly-related protein; Polycystin family receptor for egg jelly
Gene Aliases: PKDREJ
UniProt ID: (Human) Q9NTG1
Entrez Gene ID: (Human) 10343
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