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Recommended positive controls: A431.
Predicted reactivity: Mouse (96%), Rat (96%), Dog (95%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: B6P; Band 6 protein; MGC138829; Plakophilin-1
Gene Aliases: B6P; PKP1
UniProt ID: (Human) Q13835
Entrez Gene ID: (Human) 5317
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