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PLA2G12A Polyclonal Antibody

PLA2G12A Antibody in Immunocytochemistry (ICC/IF)

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PLA2G12A Antibody (16009-1-AP) in ICC/IF

Immunofluorescent analysis of HEK-293 cells using 16009-1-AP (PLA2G12A antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

PLA2G12A Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Product Details

16009-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:20-1:200

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PLA2G12A Fusion Protein Ag8722 (23-189 aa encoded by BC017218)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.27 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: QEQAQTTDW RATLKTIRNG VHKIDTYLNA ALDLLGGEDG LCQYKCSDGS KPFPRYGYKP SPPNGCGSPL FGVHLNIGIP SLTKCCNQHD RCYETCGKSK NDCDEEFQYC LSKICRDVQK TLGLTQHVQA CETTVELLFD SVIHLGCKPY LDSQRAACRC HYEEKTDL (23-189 aa encoded by BC017218 )

Target Information

Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Therapeutic effect of irbesartan combined with atorvastatin calcium in the treatment of rats with coronary heart disease.

Experimental and therapeutic medicine

Li T,Yao W

Thu Nov 01 00:00:00 UTC 2018

Quantitative trait locus mapping in mice identifies phospholipase Pla2g12a as novel atherosclerosis modifier.

Atherosclerosis

Nicolaou A,Northoff BH,Sass K,Ernst J,Kohlmaier A,Krohn K,Wolfrum C,Teupser D,Holdt LM

Sun Oct 01 00:00:00 UTC 2017

Quantitative trait locus mapping in mice identifies phospholipase Pla2g12a as novel atherosclerosis modifier.

Atherosclerosis

Nicolaou A,Northoff BH,Sass K,Ernst J,Kohlmaier A,Krohn K,Wolfrum C,Teupser D,Holdt LM

Sun Oct 01 00:00:00 UTC 2017

Quantitative trait locus mapping in mice identifies phospholipase Pla2g12a as novel atherosclerosis modifier.

Atherosclerosis

Nicolaou A,Northoff BH,Sass K,Ernst J,Kohlmaier A,Krohn K,Wolfrum C,Teupser D,Holdt LM

Sun Oct 01 00:00:00 UTC 2017

Quantitative trait locus mapping in mice identifies phospholipase Pla2g12a as novel atherosclerosis modifier.

Atherosclerosis

Nicolaou A,Northoff BH,Sass K,Ernst J,Kohlmaier A,Krohn K,Wolfrum C,Teupser D,Holdt LM

Sun Oct 01 00:00:00 UTC 2017

The expression of groups IIE and V phospholipase A2 is associated with an increased expression of osteogenic molecules in human calcified aortic valves.

Journal of atherosclerosis and thrombosis

Suzuki K,Takahashi S,Watanabe K,Fujioka D,Nakamura T,Obata JE,Kawabata K,Katoh R,Matsumoto M,Kugiyama K

Thu Sep 03 00:00:00 UTC 2015

The expression of groups IIE and V phospholipase A2 is associated with an increased expression of osteogenic molecules in human calcified aortic valves.

Journal of atherosclerosis and thrombosis

Suzuki K,Takahashi S,Watanabe K,Fujioka D,Nakamura T,Obata JE,Kawabata K,Katoh R,Matsumoto M,Kugiyama K

Thu Sep 03 00:00:00 UTC 2015

Phospholipase A2 expression in coronary thrombus is increased in patients with recurrent cardiac events after acute myocardial infarction.

International journal of cardiology

Takahashi S,Suzuki K,Watanabe Y,Watanabe K,Fujioka D,Nakamura T,Obata JE,Kawabata K,Mishina H,Kugiyama K

Wed Oct 09 00:00:00 UTC 2013

Phospholipase A2 expression in coronary thrombus is increased in patients with recurrent cardiac events after acute myocardial infarction.

International journal of cardiology

Takahashi S,Suzuki K,Watanabe Y,Watanabe K,Fujioka D,Nakamura T,Obata JE,Kawabata K,Mishina H,Kugiyama K

Wed Oct 09 00:00:00 UTC 2013

Bioinformatics

Protein Aliases: group XII secreted phospholipase A2; group XII-1 phospholipase A2; group XIIA secreted phospholipase A2; Group XIIA secretory phospholipase A2; GXII sPLA2; Phosphatidylcholine 2-acylhydrolase 12A; phospholipase A2, group XII; phospholipase A2, group XIIA; sPLA2-XII

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Gene Aliases: 2310004B05Rik; FKSG38; GXII; GXII-1; GXII-1-PLA2; mGXII-1; PLA2G12; PLA2G12A; ROSSY; UNQ2519/PRO6012

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UniProt ID: (Human) Q9BZM1, (Mouse) Q9EPR2

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Entrez Gene ID: (Human) 81579, (Rat) 362039, (Mouse) 66350

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Function(s)

phospholipase A2 activity calcium ion binding calcium-dependent phospholipase A2 activity hydrolase activity metal ion binding

Process(es)

lipid catabolic process phosphatidic acid biosynthetic process biological_process phosphatidylglycerol acyl-chain remodeling phosphatidylinositol acyl-chain remodeling phosphatidylserine acyl-chain remodeling phosphatidylcholine acyl-chain remodeling phosphatidylethanolamine acyl-chain remodeling lipid metabolic process phospholipid metabolic process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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PLA2G12A Polyclonal Antibody

PLA2G12A Antibody (16009-1-AP) in ICC/IF

Product Details

16009-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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