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Immunogen sequence: MGSSEVSIIP GLQKEEKAAV ERRRLHVLKA LKKLRIEADE APVVAVLGSG GGLRAHIACL GVLSEMKEQG LLDAVTYLAG VSGSTWAISS LYTNDGDMEA LEADLKHRFT RQEWDLAKSL QKTIQAARSE NYSLTDFWAY MVISKQTREL PESHLSNMKK PVEEGTLPYP IFAAIDNDLQ PSWQEARAP; Positive Samples: THP-1; Cellular Location: Lipid-anchor, Membrane
This gene encodes a protein which is a member of the phospholipase A2 enzyme family which hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids, both of which serve as precursors in the production of signaling molecules. The encoded protein has been shown to be a calcium-independent and membrane bound enzyme. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009].
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Protein Aliases: cPLA2-gamma; Cytosolic lysophospholipase; Cytosolic lysophospholipid O-acyltransferase; Cytosolic phospholipase A2 gamma; DKFZp586C0423; FLJ42247; FLJ44164; Phospholipase A2 group IVC; phospholipase A2, group IVC (cytosolic, calcium-independent)
Gene Aliases: CPLA2-gamma; PLA2G4C
UniProt ID: (Human) Q9UP65
Entrez Gene ID: (Human) 8605
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