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Abnova
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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MEPAGEKDEP LSVKHGRPMK CPSQESPYLF SYRNSNYLTR LQKPQDKLEV REGAEIRCPD KDPSDTVPTS VHRLKPADIN VIGALGDSLT AGNGAGSTPG NVLDVLTQYR GLSWSVGGDE NIGTVTTLAN ILREFNPSLK GFSVGTGKET SPNAFLNQAV AGGRAEDLPV QARRLVDLMK NDTRIHFQED WKIITLFIGG NDLCDFCNDL VHYSPQNFTD NIGKALDILH AEVPRAFVNL VTVLEIVNLR ELYQEKKVYC PRMILRSLCP CVLKFDDNST ELATLIEFNK KFQEKTHQLI ESGRYDTRED FTVVVQPFFE NVDMPKTSEG LPDNSFFAPD CFHFSSKSHS RAASALWNNM LEPVGQKTTR HKFENKINIT CPNQVQPFLR TYKNSMQGHG TWLPCRDRAP SALHPTSVHA LRPADIQVVA ALGDSLTAGN GIGSKPDDLP DVTTQYRGLS YRESKPGFLS DSWVSKSNRK CTRKAPNP
This gene encodes a membrane-associated phospholipase that displays lysophospholipase and phospholipase A2 activities through removal of sn-1 and sn-2 fatty acids of glycerophospholipids. In addition, it displays lipase and retinyl ester hydrolase activities. The encoded protein is highly conserved and is composed of a large, glycosylated extracellular domain composed of four tandem homologous domains, followed by a hydrophobic segment that anchors the enzyme to the membrane and a short C-terminal cytoplasmic tail. This gene has been identified as a candidate rheumatoid arthritis risk gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Lysophospholipase; Phospholipase A2; Phospholipase B; Phospholipase B/lipase; Phospholipase B1, membrane-associated; PLB/LIP; Triacylglycerol lipase
Gene Aliases: hPLB; PLB; PLB/LIP; PLB1
UniProt ID: (Human) Q6P1J6
Entrez Gene ID: (Human) 151056
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