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PLCB3 Antibody (PA5-120077) in IHC (P)
Immunohistochemistry analysis of PLCB3 in paraffin-embedded rat brain. Samples were incubated with PLCB3 Polyclonal antibody (Product # PA5-120077) using a dilution of 1:100 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Product Details
PA5-120077
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1010-1234 of human PLC beta 3 (PLCB3) (NP_001303243.1).
Conjugate
Form
Liquid
Concentration
1.65 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2913649
Product Specific Information
Positive test controls include: OVCAR8, Mouse lung, Rat lung. The target is usually found in the following locations: Membrane, Peripheral membrane protein.
Immunogen sequence: GALGGAADVE DTKEGEDEAK RYQEFQNRQV QSLLELREAQ VDAEAQRRLE HLRQALQRLR EVVLDANTTQ FKRLKEMNER EKKELQKILD RKRHNSISEA KMRDKHKKEA ELTEINRRHI TESVNSIRRL EEAQKQRHDR LVAGQQQVLQ QLAEEEPKLL AQLAQECQEQ RARLPQEIRR SLLGEMPEGL GDGPLVACAS NGHAPGSSGH LSGADSESQE ENTQL
Target Information
PLCB3 encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3; EC 3.1.4.11; Phosphoinositide phospholipase C-beta-3; phosphoinositide-specific phospholipase c; phospholipase C beta 3; phospholipase C, beta 3 (phosphatidylinositol-specific); Phospholipase C-beta-3; PLC beta 3; PLC-beta-3; PLC-beta3; PLCbeta3
Gene Aliases: mKIAA4098; PLCB3
UniProt ID: (Human) Q01970, (Mouse) P51432
Entrez Gene ID: (Human) 5331, (Rat) 29322, (Mouse) 18797
regulation of systemic arterial blood pressure
post-Golgi vesicle-mediated transport
G-protein coupled receptor signaling pathway
Wnt signaling pathway, calcium modulating pathway
chemical synaptic transmission
lipid catabolic process
intracellular signal transduction
inositol phosphate metabolic process
cell-cell adhesion
phospholipid catabolic process
lipid metabolic process
signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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