Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 4
PLCB3 Antibody (PA5-78109) in WB
Western blot analysis of PLCB3 in various whole cell extracts (30 µg). Samples were incubated with PLCB3 polyclonal antibody (Product # PA5-78109) using a dilution of 1:1,000 followed by HRP-conjugated anti-rabbit IgG. Separated by 5% SDS-PAGE. Competitors antibody diluted at 1:1,000.
Product Details
PA5-78109
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human PLCB3. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.0 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2736445
Product Specific Information
Positive Control: 293T, A431, HeLa, PC3, Neuro2A, CD830, NIH-3T3, Raw264.7, C2C12, PC-12, Rat-2, MCF-7, MDA-MB-231
Predicted Reactivity: Zebrafish (83%), Xenopus laevis (83%), Bovine (99%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PLCB3 encodes a member of the phosphoinositide phospholipase C beta enzyme family that catalyze the production of the secondary messengers diacylglycerol and inositol 1,4,5-triphosphate from phosphatidylinositol in G-protein-linked receptor-mediated signal transduction. Alternative splicing results in multiple transcript variants.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3; EC 3.1.4.11; Phosphoinositide phospholipase C-beta-3; phosphoinositide-specific phospholipase c; phospholipase C beta 3; phospholipase C, beta 3 (phosphatidylinositol-specific); Phospholipase C-beta-3; PLC beta 3; PLC-beta-3; PLC-beta3; PLCbeta3
Gene Aliases: mKIAA4098; PLCB3
UniProt ID: (Human) Q01970, (Mouse) P51432
Entrez Gene ID: (Human) 5331, (Rat) 29322, (Mouse) 18797
regulation of systemic arterial blood pressure
post-Golgi vesicle-mediated transport
G-protein coupled receptor signaling pathway
Wnt signaling pathway, calcium modulating pathway
chemical synaptic transmission
lipid catabolic process
intracellular signal transduction
inositol phosphate metabolic process
cell-cell adhesion
phospholipid catabolic process
lipid metabolic process
signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support