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PLD1 Antibody (PA5-102918) in IHC (P)
Immunohistochemistry analysis of PLD1 in mouse brain tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with PLD1 polyclonal antibody (Product # PA5-102918) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-102918
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PLD1(Accession Q13393), corresponding to amino acid residues P536-Y586.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2852296
Product Specific Information
Antibody detects endogenous levels of total PLD1.
Target Information
Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis (Hammond et al., 1995).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Choline phosphatase 1; hPLD1; mPLD1; phophatidylcholine-specific; Phoshpolipase D gene 1 probably with two splicing variants A and B; Phosphatidylcholine-hydrolyzing phospholipase D1; phospholipase D gene 1, probably with two splicing variants A and B; Phospholipase D1; phospholipase D1, phosphatidylcholine-specific; PLD 1; rPLD1
Gene Aliases: AA536939; C85393; PLD1; Pld1a; Pld1b; Plda; Pldb
UniProt ID: (Human) Q13393, (Rat) P70496
Entrez Gene ID: (Human) 5337, (Rat) 25096, (Mouse) 18805
phosphatidic acid biosynthetic process
metabolic process
phospholipid biosynthetic process
phospholipid catabolic process
positive regulation of cell migration
regulation of microvillus assembly
response to peptide hormone
defense response to Gram-positive bacterium
lipid metabolic process
lipid catabolic process
regulation of cell migration
inositol lipid-mediated signaling
regulation of phagocytosis
chemotaxis
small GTPase mediated signal transduction
Ras protein signal transduction
cell motility
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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