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Invitrogen
PLD1 Polyclonal Antibody
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Product Details
PA5-79828
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E.coli-derived human PLD1 recombinant protein (Position: M1-H330).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2746943
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Mouse Cardiac Muscle Tissue, 22RV1 whole cell, HELA whole cell.
Target Information
Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis (Hammond et al., 1995).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Choline phosphatase 1; hPLD1; mPLD1; phophatidylcholine-specific; Phosphatidylcholine-hydrolyzing phospholipase D1; Phospholipase D1; phospholipase D1, phosphatidylcholine-specific; PLD 1
Gene Aliases: AA536939; C85393; PLD1; Pld1a; Pld1b
UniProt ID: (Human) Q13393
Entrez Gene ID: (Human) 5337, (Mouse) 18805
lipid metabolic process
phosphatidic acid biosynthetic process
phospholipid biosynthetic process
phospholipid catabolic process
lipid catabolic process
regulation of cell migration
positive regulation of cell migration
regulation of microvillus assembly
response to peptide hormone
inositol lipid-mediated signaling
regulation of phagocytosis
defense response to Gram-positive bacterium
chemotaxis
small GTPase mediated signal transduction
Ras protein signal transduction
cell motility
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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