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Invitrogen
PLD1 Polyclonal Antibody
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Product Details
PA5-90209
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 875-1036 of human PLD1 (NP_0011235531)
Conjugate
Form
Liquid
Concentration
1.57 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2805961
Product Specific Information
Immunogen sequence: NINDRSMLGK RDSEMAVIVQ DTETVPSVMD GKEYQAGRFA RGLRLQCFRV VLGYLDDPSE DIQDPVSDKF FKEVWVSTAA RNATIYDKVF RCLPNDEVHN LIQLRDFINK PVLAKEDPIR AEEELKKIRG FLVQFPFYFL SEESLLPSVG TKEAIVPMEV WT; Positive Samples: HeLa, HT-29, LO2; Cellular Location: Cytoplasm, Cytoplasmic side, Endoplasmic reticulum membrane, Golgi apparatus membrane, Late endosome membrane, Lipid-anchor, perinuclear region
Target Information
Phosphatidylcholine (PC)-specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. A range of agonists acting through G protein-coupled receptors and receptor tyrosine kinases stimulate this hydrolysis. PC-specific PLD activity has been implicated in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis (Hammond et al., 1995).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Choline phosphatase 1; hPLD1; phophatidylcholine-specific; Phosphatidylcholine-hydrolyzing phospholipase D1; Phospholipase D1; phospholipase D1, phosphatidylcholine-specific; PLD 1
Gene Aliases: PLD1
UniProt ID: (Human) Q13393
Entrez Gene ID: (Human) 5337
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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