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Abnova
PLEK Polyclonal Antibody, MaxPab™
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Product Details
H00005341-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PLEK (NP_002655.1, 1 a.a. approximately 350 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MEPKRIREGY LVKKGSVFNT WKPMWVVLLE DGIEFYKKKS DNSPKGMIPL KGSTLTSPCQ DFGKRMFVFK ITTTKQQDHF FQAAFLEERD AWVRDINKAI KCIEGGQKFA RKSTRRSIRL PETIDLGALY LSMKDTEKGI KELNLEKDKK IFNHCFTGNC VIDWLVSNQS VRNRQEGLMI ASSLLNEGYL QPAGDMSKSA VDGTAENPFL DNPDAFYYFP DSGFFCEENS SDDDVILKEE FRGVIIKQGC LLKQGHRRKN WKVRKFILRE DPAYLHYYDP AGAEDPLGAI HLRGCVVTSV ESNSNGRKSE EENLFEIITA DEVHYFLQAA TPKERTEWIK AIQMASRTGK
Target Information
Major protein kinase C substrate of platelets.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ27168; p47; Platelet 47 kDa protein; Pleckstrin
Gene Aliases: P47; PLEK
UniProt ID: (Human) P08567
Entrez Gene ID: (Human) 5341
hematopoietic progenitor cell differentiation
platelet degranulation
vesicle docking involved in exocytosis
integrin-mediated signaling pathway
positive regulation of platelet activation
negative regulation of inositol phosphate biosynthetic process
positive regulation of inositol-polyphosphate 5-phosphatase activity
cell projection organization
positive regulation of actin filament depolymerization
phospholipase C-inhibiting G-protein coupled receptor signaling pathway
cortical actin cytoskeleton organization
ruffle organization
actin cytoskeleton reorganization
positive regulation of actin filament bundle assembly
positive regulation of integrin activation
negative regulation of G-protein coupled receptor protein signaling pathway
phosphatidylinositol metabolic process
negative regulation of calcium-mediated signaling
regulation of cell diameter
thrombin receptor signaling pathway
platelet aggregation
protein kinase C signaling
protein secretion by platelet
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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