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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • Pleckstrin Antibodies

          Proteintech

          PLEK Monoclonal Antibody (1D5C2)

          View all (34) Pleckstrin antibodies

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          Datasheet
          Protocols
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          Datasheet
          Protocols
          Questions & Answers

          Cite PLEK Monoclonal Antibody (1D5C2)

          • Antibody Testing Data (9)
          PLEK Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          PLEK Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 9

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          PLEK Antibody (66431-1-IG) in IHC (P)

          Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using 66431-1-IG ( PLEK Antibody) at dilution of 1:500 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PLEK Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PLEK Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PLEK Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          PLEK Antibody in Immunohistochemistry (PFA fixed) (IHC (PFA))
          PLEK Antibody in Western Blot (WB)
          PLEK Antibody in Western Blot (WB)
          PLEK Antibody in Western Blot (WB)
          PLEK Antibody in Western Blot (WB)
          PLEK Antibody in Western Blot (WB)

          Product Details

          66431-1-IG

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:2,000-1:20,000
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:500
          -

          Immunohistochemistry (PFA fixed) (IHC (PFA))

          1:500
          -
          Product Specifications

          Species Reactivity

          Human, Pig

          Host/Isotype

          Mouse / IgG1

          Class

          Monoclonal

          Type

          Antibody

          Clone

          1D5C2

          Immunogen

          PLEK Fusion Protein Ag3187 (1-350 aa encoded by BC018549)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated
          • CoraLite 594
          • CoraLite Plus 488
          • Request custom conjugation

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein G

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MEPKRIREG YLVKKGSVFN TWKPMWVVLL EDGIEFYKKK SDNSPKGMIP LKGSTLTSPC QDFGKRMFVF KITTTKQQDH FFQAAFLEER DAWVRDIKKA IKCIEGGQKF ARKSTRRSIR LPETIDLGAL YLSMKDTEKG IKELNLEKDK KIFNHCFTGN CVIDWLVSNQ SVRNRQEGLM IASSLLNEGY LQPAGDMSKS AVDGTAENPF LDNPDAFYYF PDSGFFCEEN SSDDDVILKE EFRGVIIKQG CLLKQGHRRK NWKVRKFILR EDPAYLHYYD PAGAEDPLGA IHLRGCVVTS VESNSNGRKS EEENLFEIIT ADEVHYFLQA ATPKERTEWI KAIQMASRTG K (1-350 aa encoded by BC018549)

          Target Information

          Major protein kinase C substrate of platelets.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: FLJ27168; p47; Platelet 47 kDa protein; Pleckstrin

          View more View less

          Gene Aliases: P47; PLEK

          View more View less

          UniProt ID: (Human) P08567

          View more View less

          Entrez Gene ID: (Human) 5341

          View more View less

          Function(s)
          protein kinase C binding protein binding protein homodimerization activity phosphatidylinositol-3,4-bisphosphate binding
          Process(es)
          hematopoietic progenitor cell differentiation platelet degranulation vesicle docking involved in exocytosis integrin-mediated signaling pathway positive regulation of platelet activation negative regulation of inositol phosphate biosynthetic process positive regulation of inositol-polyphosphate 5-phosphatase activity cell projection organization positive regulation of actin filament depolymerization phospholipase C-inhibiting G-protein coupled receptor signaling pathway cortical actin cytoskeleton organization ruffle organization actin cytoskeleton reorganization positive regulation of actin filament bundle assembly positive regulation of integrin activation negative regulation of G-protein coupled receptor protein signaling pathway phosphatidylinositol metabolic process negative regulation of calcium-mediated signaling regulation of cell diameter thrombin receptor signaling pathway platelet aggregation protein kinase C signaling protein secretion by platelet
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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