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OriGene
PLEK Monoclonal Antibody (OTI2D11), TrueMAB™
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FIGURE: 1 / 3
PLEK Antibody (TA500900) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PLEK (RC203780, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PLEK. Positive lysates LY419171 (100 µg) and LC419171 (20 µg) can be purchased separately from OriGene.
Product Details
TA500900
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI2D11
Immunogen
Full length human recombinant protein of human PLEK produced in HEK293T cell.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 1% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Major protein kinase C substrate of platelets.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ27168; p47; Platelet 47 kDa protein; Pleckstrin
Gene Aliases: P47; PLEK
UniProt ID: (Human) P08567
Entrez Gene ID: (Human) 5341
hematopoietic progenitor cell differentiation
platelet degranulation
vesicle docking involved in exocytosis
integrin-mediated signaling pathway
positive regulation of platelet activation
negative regulation of inositol phosphate biosynthetic process
positive regulation of inositol-polyphosphate 5-phosphatase activity
cell projection organization
positive regulation of actin filament depolymerization
phospholipase C-inhibiting G-protein coupled receptor signaling pathway
cortical actin cytoskeleton organization
ruffle organization
actin cytoskeleton reorganization
positive regulation of actin filament bundle assembly
positive regulation of integrin activation
negative regulation of G-protein coupled receptor protein signaling pathway
phosphatidylinositol metabolic process
negative regulation of calcium-mediated signaling
regulation of cell diameter
thrombin receptor signaling pathway
platelet aggregation
protein kinase C signaling
protein secretion by platelet
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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