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Proteintech
PLEKHA8 Polyclonal Antibody
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Product Details
15410-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PLEKHA8 Fusion Protein Ag7677 (1-350 aa encoded by BC002838)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MEGVLYKWT NYLSGWQPRW FLLCGGILSY YDSPEDAWKG CKGSIQMAVC EIQVHSVDNT RMDLIIPGEQ YFYLKARSVA ERQRWLVALG SAKACLTDSR TQKEKEFAEN TENLKTKMSE LRLYCDLLVQ QVDKTKEVTT TGVSNSEEGI DVGTLLKSTC NTFLKTLEEC MQIANAAFTS ELLYRTPPGS PQLAMLKSSK MKHPIIPIHN SLERQMELST CENGSLNMEI NGEEEILMKN KNSLYLKSAE IDCSISSEEN TDDNITVQGE IRKEDGMENL KNHDNNLTQS GSDSSCSPEC LWEEGKEVIP TFFSTMNTSF SDIELLEDSG IPTEAFLASC YAVVPVLDKL G (1-350 aa encoded by BC002838)
Target Information
Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans-Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FAPP-2; hFAPP2; MGC3358; PH domain-containing family A member 8; Phosphatidylinositol-four-phosphate adapter protein 2; phosphoinositol 4-phosphate adapter protein 2; pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8; Pleckstrin homology domain-containing family A member 8; Serologically defined breast cancer antigen NY-BR-86
Gene Aliases: 6330400G01; AA517676; BC052360; FAPP-2; FAPP2; PLEKHA8; RGD1563940
UniProt ID: (Human) Q96JA3, (Mouse) Q80W71, (Rat) D3ZY60
Entrez Gene ID: (Human) 84725, (Mouse) 231999, (Rat) 500132
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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