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Abnova
PLK3 Polyclonal Antibody, MaxPab™
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Product Details
H00001263-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PLK3 (NP_004064.2, 1 a.a. approximately 646 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.74 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MEPAAGFLSP RPFQRAAAAP APPAGPGPPP SALRGPELEM LAGLPTSDPG RLITDPRSGR TYLKGRLLGK GGFARCYEAT DTETGSAYAV KVIPQSRVAK PHQREKILNE IELHRDLQHR HIVRFSHHFE DADNIYIFLE LCSRKSLAHI WKARHTLLEP EVRYYLRQIL SGLKYLHQRG ILHRDLKLGN FFITENMELK VGDFGLAARL EPPEQRKKTI CGTPNYVAPE VLLRQGHGPE ADVWSLGCVM YTLLCGSPPF ETADLKETYR CIKQVHYTLP ASLSLPARQL LAAILRASPR DRPSIDQILR HDFFTKGYTP DRLPISSCVT VPDLTPPNPA RSLFAKVTKS LFGRKKKSKN HAQERDEVSG LVSGLMRTSV GHQDARPEAP AASGPAPVSL VETAPEDSSP RGTLASSGDG FEEGLTVATV VESALCALRN CIAFMPPAEQ NPAPLAQPEP LVWVSKWVDY SNKFGFGYQL SSRRVAVLFN DGTHMALSAN RKTVHYNPTS TKHFSFSVGA VPRALQPQLG ILRYFASYME QHLMKGGDLP SVEEVEVPAP PLLLQWVKTD QALLMLFSDG TVQVNFYGDH TKLILSGWEP LLVTFVARNR SACTYLASHL RQLGCSPDLR QRLRYALRLL RDRSPA
Target Information
PLK3 is a member of the polo family of serine/threonine kinases. PLK3 is involved in the regulation of M phase in the cell cycle. CNK contains both a catalytic domain and a putative regulatory domain. It may play a role in regulation of cell cycle progression and tumorigenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cytokine-inducible serine/threonine-protein kinase; FGF-inducible kinase; PLK-3; Polo-like kinase 3; Proliferation-related kinase; Serine/threonine-protein kinase PLK3
Gene Aliases: CNK; FNK; PLK-3; PLK3; PRK
UniProt ID: (Human) Q9H4B4
Entrez Gene ID: (Human) 1263
G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
response to reactive oxygen species
protein phosphorylation
apoptotic process
response to osmotic stress
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
mitotic cell cycle checkpoint
endomitotic cell cycle
response to radiation
cytoplasmic microtubule organization
regulation of cytokinesis
negative regulation of apoptotic process
protein kinase B signaling
mitotic G1/S transition checkpoint
regulation of cell division
Golgi disassembly
positive regulation of intracellular protein transport
regulation of signal transduction by p53 class mediator
positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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