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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • PLOD2 Antibodies

          Proteintech

          PLOD2 Polyclonal Antibody

          56 References
          View all (20) PLOD2 antibodies

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          Datasheet
          Protocols
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          Datasheet
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          Cite PLOD2 Polyclonal Antibody

          • Antibody Testing Data (24)
          PLOD2 Antibody in Immunocytochemistry (ICC/IF)
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          PLOD2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 24

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          PLOD2 Antibody (21214-1-AP) in ICC/IF

          Immunofluorescent analysis of Hela cells, using PLOD2 antibody 21214-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PLOD2 Antibody in Immunocytochemistry (ICC/IF)
          PLOD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PLOD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PLOD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PLOD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PLOD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PLOD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PLOD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PLOD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PLOD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PLOD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PLOD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PLOD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PLOD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PLOD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PLOD2 Antibody in Western Blot (WB)
          PLOD2 Antibody in Western Blot (WB)
          PLOD2 Antibody in Western Blot (WB)
          PLOD2 Antibody in Western Blot (WB)
          PLOD2 Antibody in Western Blot (WB)
          PLOD2 Antibody in Western Blot (WB)
          PLOD2 Antibody in Western Blot (WB)
          PLOD2 Antibody in Flow Cytometry (Flow)
          PLOD2 Antibody in Immunoprecipitation (IP)

          Product Details

          21214-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          View 33 publications 33 publications

          Immunohistochemistry (IHC)

          -
          View 18 publications 18 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:100-1:400
          -

          Immunocytochemistry (ICC/IF)

          1:10-1:100
          View 5 publications 5 publications

          Flow Cytometry (Flow)

          0.2 µg/1x10^6 cells
          -

          Immunoprecipitation (IP)

          0.5-4.0 µg
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Human, Mouse, Zebrafish

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          PLOD2-Specific Fusion Protein Ag15614 (459-540 aa encoded by BC037169)

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.21 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          This antibody is specific to PLOD2.

          Immunogen sequence: PYMANVYLI KGKTLRSEMN ERNYFVRDKL DPDMALCRNA REMTLQREKD SPTPETFQML SPPKGVFMYI SNRHEFGRLL STA (459-540 aa encoded by BC037169)

          Target Information

          The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: LH2; lysine hydroxylase 2; lysyl hydroxlase 2; Lysyl hydroxylase 2; Procollagen-lysine 2-oxoglutarate 5-dioxygenase (Lysine hydroxylase) 2; procollagen-lysine 5-dioxygenase; Procollagen-lysine, 2-oxoglutarate 5-dioxygenase (Lysine hydroxylase) 2; procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2; Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2; telopeptide lysyl hydroxylase

          View more View less

          Gene Aliases: BRKS2; D530025C14Rik; LH2; Plod-2; PLOD2; TLH

          View more View less

          UniProt ID: (Human) O00469, (Mouse) Q9R0B9

          View more View less

          Entrez Gene ID: (Human) 5352, (Rat) 300901, (Mouse) 26432

          View more View less

          Function(s)
          iron ion binding procollagen-lysine 5-dioxygenase activity L-ascorbic acid binding molecular_function oxidoreductase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors metal ion binding dioxygenase activity
          Process(es)
          response to hypoxia cellular response to hormone stimulus oxidation-reduction process cellular protein modification process mitophagy in response to mitochondrial depolarization
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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