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Invitrogen
PLSCR3 Recombinant Rabbit Monoclonal Antibody (4V2P5)
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FIGURE: 1 / 2
PLSCR3 Antibody (MA5-55368) in WB
Western Blot analysis of various lysates using PLSCR3 Recombinant Monoclonal Antibody (Product # MA5-55368) at 1:1,000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
MA5-55368
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
4V2P5
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PLSCR3.
Conjugate
Form
Liquid
Concentration
2 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
RRID
AB_3667609
Product Specific Information
Immunogen Sequence: MAGYLPPKGY APSPPPPYPV TPGYPEPALH PGPGQAPVPA QVPAPAPGFA LFPSPGPVAL GSAAPFLPLP GVPSGLEFLV QIDQILIHQK AERVETFLGW
Target Information
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ca 2+ dependent phospholipid scramblase 3; Ca(2+)-dependent phospholipid scramblase 3; Phospholipid scramblase 3; PL scramblase 3
Gene Aliases: 2210403O21Rik; 2610037N06Rik; ESTM3; Pls3; PLSCR3; X83310
UniProt ID: (Human) Q9NRY6, (Rat) Q6QBQ4, (Mouse) Q9JIZ9
Entrez Gene ID: (Human) 57048, (Rat) 360549, (Mouse) 70310
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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