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Invitrogen
PLUNC Polyclonal Antibody
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PLUNC Antibody (PA5-47605) in IHC (F)
Immunohistochemical analysis of PLUNC in immersion fixed frozen sections of mouse embryo nose (13 d.p.c.). Samples were incubated in PLUNC polyclonal antibody (Product # PA5-47605) using a dilution of 1.7 µg/mL overnight at 4 °C. Tissue was stained using the Anti-Sheep HRP-DAB Cell & Tissue Staining Kit (brown) and counterstained with hematoxylin (blue). Specific staining was localized to olfactory epitheli... View More
Product Details
PA5-47605
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived recombinant mouse PLUNC Ala59-Val278
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2608226
Product Specific Information
Less than 10% cross-reactivity with recombinant human PLUNC is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
PLUNC is the human homolog of murine plunc and is specifically expressed in the upper airways and nasopharyngeal regions. The exact biological function of this protein is not known, however, it has been suggested to be involved in inflammatory responses to irritants in the upper airways. It may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The exact biological function of this gene is not known, however, it has been suggested to be involved in inflammatory responses to irritants in the upper airways. It may also serve as a potential molecular marker for detection of micrometastasis in non-small-cell lung cancer. Multiple transcript variants resulting from alternative splicing in the 3' UTR have been detected, but the full-length nature of only two is known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BPI fold-containing family A member 1; LPLUNC3; LUNXNASG; Palate lung and nasal epithelium clone protein; palate, lung, and nasal epithelium associated; palate, lung, and nasal epithelium clone; palate, lung, and nasal epithelium expressed transcript; protein Plunc; short palate; SPLUNC1SPURT
Gene Aliases: Bpifa1; LUNX; NASG; Plunc; SPLUNC1; SPURT
UniProt ID: (Mouse) P97361
Entrez Gene ID: (Mouse) 18843
immune system process
antibacterial humoral response
defense response to bacterium
innate immune response
regulation of liquid surface tension
multicellular organismal water homeostasis
negative regulation of single-species biofilm formation in or on host organism
regulation of sodium ion transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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