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Invitrogen
PLXNA4 Polyclonal Antibody
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Product Details
PA5-32026
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the Extracellular domain of human Plexin A4. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2549499
Product Specific Information
Recommended positive controls: 293T, A431, Jurkat, Raji.
Predicted reactivity: Mouse (96%), Zebrafish (84%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
PLXNA4 is a protein coding gene. Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: OTTHUMP00000207245; Plexin-A4
Gene Aliases: FAYV2820; KIAA1550; PLEXA4; PLXNA4; PLXNA4A; PLXNA4B; PRO34003; UNQ2820/PRO34003
UniProt ID: (Human) Q9HCM2
Entrez Gene ID: (Human) 91584
facial nerve structural organization
glossopharyngeal nerve morphogenesis
trigeminal nerve structural organization
vagus nerve morphogenesis
postganglionic parasympathetic fiber development
branchiomotor neuron axon guidance
chemorepulsion of branchiomotor axon
anterior commissure morphogenesis
regulation of cell migration
sympathetic nervous system development
regulation of axon extension involved in axon guidance
regulation of negative chemotaxis
semaphorin-plexin signaling pathway
semaphorin-plexin signaling pathway involved in axon guidance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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