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Invitrogen
PLXNA4 Polyclonal Antibody
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Product Details
PA5-84988
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PLXNA4. Recombinant protein control fragment (Product #RP-108658).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2792137
Product Specific Information
Immunogen sequence: LNAGSNVVVM FGKQPCLFHR RSPSYIVCNT TSSDEVLEMK VSVQVDRAKI HQDLVFQYVE DPTIVRIEPE WSIVSGNTPI AVW
Target Information
PLXNA4 is a protein coding gene. Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: OTTHUMP00000207245; Plexin-A4
Gene Aliases: FAYV2820; KIAA1550; PLEXA4; PLXNA4; PLXNA4A; PLXNA4B; PRO34003; UNQ2820/PRO34003
UniProt ID: (Human) Q9HCM2
Entrez Gene ID: (Human) 91584
facial nerve structural organization
glossopharyngeal nerve morphogenesis
trigeminal nerve structural organization
vagus nerve morphogenesis
postganglionic parasympathetic fiber development
branchiomotor neuron axon guidance
chemorepulsion of branchiomotor axon
anterior commissure morphogenesis
regulation of cell migration
sympathetic nervous system development
regulation of axon extension involved in axon guidance
regulation of negative chemotaxis
semaphorin-plexin signaling pathway
semaphorin-plexin signaling pathway involved in axon guidance
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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