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Invitrogen
PLXNB3 Polyclonal Antibody
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PLXNB3 Antibody (PA5-47882) in IHC (F)
Immunohistochemical analysis of PLXNB3 in perfusion fixed frozen sections of mouse brain. Samples were incubated in PLXNB3 polyclonal antibody (Product # PA5-47882) using a dilution of 1.7 µg/mL overnight at 4 °C followed by NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to oligodendrocytes.
Product Details
PA5-47882
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
CHO-derived recombinant mouse Plexin B3 His25-Gln1235
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2576809
Product Specific Information
In direct ELISAs, approximately 38% cross-reactivity with recombinant human (rh) Plexin B3 is observed, and less than 1% cross-reactivity with rhPlexin B2 is observed.
Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.
Target Information
The protein encoded by this gene is a member of the plexin family. It functions as a receptor for semaphorin 5A, and plays a role in axon guidance, invasive growth and cell migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ76953; plexin 6; Plexin-6; Plexin-B3; plexin-B3 {ECO:0000303|PubMed:20696765}; plxnb3 {ECO:0000312|Ensembl:ENSRNOP00000053235}; Protein Plxnb3
Gene Aliases: AI451018; Kiaa1206; Plxn6; Plxnb3; RGD1560615
UniProt ID: (Mouse) Q9QY40, (Rat) D3ZLH5
Entrez Gene ID: (Mouse) 140571, (Rat) 363517
positive regulation of endothelial cell proliferation
negative regulation of cell adhesion
signal transduction
nervous system development
negative regulation of lamellipodium assembly
negative regulation of cell migration
negative regulation of GTPase activity
positive chemotaxis
cell chemotaxis
semaphorin-plexin signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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