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Invitrogen
PMA1 Monoclonal Antibody (40B7)
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FIGURE: 1 / 4
PMA1 Antibody (MA1-91567) in WB
Molecular medicine reports 2020 -
Figure 2. APOL1 expression levels and cell proliferation on non-fermentable media. (A) APOL1 inhibited yeast proliferation in non-fermentable media: HA tagged wild type and BH3-deleted (BH3) APOL1 expression was induced by galactose and cells were then shifted in liquid glycerol containing MGly media at T=0. Error bars represent standard errors on three independent experiments. (B) APOL1 protein expression ... View More
Product Details
MA1-91567
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Yeast
Published species
Yeast
Host/Isotype
Mouse
/ IgG
Class
Monoclonal
Type
Antibody
Clone
40B7
Immunogen
Yeast membrane preps.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
tissue culture supernatant
Contains
10mM sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1959827
Product Specific Information
The predicted molecular weight by western blot is 100 kDa.
Target Information
The PMA1 (Plasma Membrane ATPase 1) gene encodes a highly conserved enzyme that functions as a proton pump (H+ ATPase) in the plasma membrane of yeast and plant cells. This enzyme is essential for maintaining cellular pH and membrane potential by actively transporting protons (H+) out of the cell, using energy derived from ATP hydrolysis. In Saccharomyces cerevisiae (baker's yeast), PMA1 is vital for nutrient uptake, cell growth, and overall cellular homeostasis. The activity of PMA1 is regulated through various mechanisms, including phosphorylation and interaction with regulatory proteins. In plants, homologs of PMA1 play a crucial role in processes like stomatal opening, nutrient uptake, and stress responses. Given its fundamental role in cellular physiology, PMA1 has been a target for antifungal agents and herbicides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: H(+)-exporting P2-type ATPase PMA1; Plasma membrane ATPase 1; Proton pump 1
Gene Aliases: KTI10; PMA1; YGL008C
UniProt ID: (Baker's yeast) P05030
Entrez Gene ID: (Baker's yeast) 852876
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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