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Abnova
PMM2 Monoclonal Antibody (2E9)
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Product Details
H00005373-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
2E9
Immunogen
PMM2 (NP_000294, 47 a.a. approximately 111 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: SDFEKVQEQL GNDVVEKYDY VFPENGLVAY KDGKLLCRQN IQSHLGEALI QDLINYCLSY IAKIK
Target Information
The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: mannose-6-phosphate isomerase; Phosphomannomutase 2; phosphomannose isomerase 1; PMM 2
Gene Aliases: CDG1; CDG1a; CDGS; PMI; PMI1; PMM 2; PMM2
UniProt ID: (Human) O15305
Entrez Gene ID: (Human) 5373
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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