Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
PNLDC1 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
25559-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Insect
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PNLDC1 Fusion Protein Ag22074 (19-371 aa encoded by BC112246)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EFTGLRSNL SGPQQISLFD LPSEWYLKTR QSVQQFTVCQ IGLSVFSAIE GEANKYIAHS CNFYLFPTTF GILDSEFSFQ ASSVQFLNQY GFNYNKFLKN GIPYMNEEQE KKIRHDILTG NWRVRSSPDK DQIKVVIDEV TRWLELAKEG DWMTLPGITG FQAFEVQLVL RQALPNIWTV LKDEGVVVKK VSKQHRWYLQ NTSCDRESCW KENILLSARG FSVFFQMLVK AQKPLVGHNM MMDLLHLHEK FFRPLPESYD QFKQNIHSLF PVLIDTKSVT KDIWKEMNFP RVSNLSEVYE VLNSDLNPTK NSGPEIVHAS RCEKYVETKC PHEAAYDAFL CGSVLLKVAH LLLQ (19-371 aa encoded by BC112246)
Target Information
3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails (PubMed:27515512). Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development (PubMed:27515512). May act as a regulator of multipotency in embryonic stem cells. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: HsPNLDC1; PARN-like domain-containing protein 1; poly(A)-specific ribonuclease (PARN)-like domain containing 1; Poly(A)-specific ribonuclease domain-containing protein 1; poly(A)-specific ribonuclease PARN-like domain-containing protein 1; Poly(A)-specific ribonuclease PNLDC1
Gene Aliases: Gm313; PNLDC1
UniProt ID: (Human) Q8NA58, (Mouse) B2RXZ1
Entrez Gene ID: (Human) 154197, (Mouse) 240023
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support