Abnova

PNPLA3 Polyclonal Antibody, MaxPab™

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

H00080339-D01P

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PNPLA3 (AAH65195.1, 1 a.a. approximately 481 a.a) full-length human protein.
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: MYDAERGWSL SFAGCGFLGF YHVGATRCLS EHAPHLLRDA RMLFGASAGA LHCVGVLSGI PLEQTLQVLS DLVRKARSRN IGIFHPSFNL SKFLRQGLGK CLPANVHQLI SGKIGISLTR VSDGENVLVS DFRSKDEVVD ALVCSCFMPF YSGLIPPSFR GVRYVDGGVS DNVPFIDAKT TITVSPFYGE YDICPKVKST NFLHVDITKL SLRLCTGNLY LLSRAFVPPD LKVLGEICLR GYLDAFRFLE EKGICNRPQP GLKSSSEGMD PEVAMPSWAN MSLDSSPESA ALAVRLEGDE LLDHLRLSIL PWDESILDTL SPRLATALSE EMKDKGGYMS KICNLLPIRI MSYVMLPCTL PVESAIAIVQ RLVTWLPDMP DDVLWLQWVT SQVFTRVLMC LLPASRSQMP VSSQQASPCT PEQDWPCWTP CSPEGCPAET KAEATPRSIL RSSLNFFLGN KVPAGAEGLS TFPSFSLEKS L

Target Information

The protein encoded by this gene is a triacylglycerol lipase that mediates triacylglycerol hydrolysis in adipocytes. The encoded protein, which appears to be membrane bound, may be involved in the balance of energy usage/storage in adipocytes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3; acylglycerol O-acyltransferase; Acylglycerol transacylase; Adiponutrin; ADPN; Calcium-independent phospholipase A2-epsilon; iPLA2-epsilon; iPLA2epsilon; Lysophosphatidic acid acyltransferase; patatin-like phospholipase domain containing 3; Patatin-like phospholipase domain-containing protein 3

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Gene Aliases: ADPN; C22orf20; iPLA(2)epsilon; PNPLA3

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UniProt ID: (Human) Q9NST1, (Mouse) Q91WW7

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Entrez Gene ID: (Human) 80339, (Mouse) 116939

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Function(s)
lipoprotein lipase activity phospholipase A2 activity triglyceride lipase activity acylglycerol O-acyltransferase activity mono-olein transacylation activity diolein transacylation activity dihydrolipoamide branched chain acyltransferase activity sterol O-acyltransferase activity N-acetyltransferase activity O-acyltransferase activity palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity carnitine O-acyltransferase activity acetyltransferase activity C-acyltransferase activity palmitoyltransferase activity N-acyltransferase activity serine O-acyltransferase activity O-acetyltransferase activity O-octanoyltransferase activity octanoyltransferase activity O-palmitoyltransferase activity S-acyltransferase activity S-acetyltransferase activity S-malonyltransferase activity malonyltransferase activity C-palmitoyltransferase activity transferase activity transferase activity, transferring acyl groups succinyltransferase activity N-succinyltransferase activity O-succinyltransferase activity S-succinyltransferase activity sinapoyltransferase activity O-sinapoyltransferase activity hydrolase activity peptidyl-lysine N6-myristoyltransferase activity peptidyl-lysine N6-palmitoyltransferase activity benzoyl acetate-CoA thiolase activity 3-hydroxybutyryl-CoA thiolase activity 3-ketopimelyl-CoA thiolase activity N-palmitoyltransferase activity myristoyltransferase activity acyl-CoA N-acyltransferase activity protein-cysteine S-myristoyltransferase activity protein-cysteine S-acyltransferase activity dihydrolipoamide S-acyltransferase activity glucosaminyl-phosphotidylinositol O-acyltransferase activity ergosterol O-acyltransferase activity lanosterol O-acyltransferase activity naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity 2-methylhexanoyl-CoA C-acetyltransferase activity butyryl-CoA 2-C-propionyltransferase activity 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity L-2-aminoadipate N-acetyltransferase activity UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity keto acid formate lyase activity Ras palmitoyltransferase activity azetidine-2-carboxylic acid acetyltransferase activity peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor acetyl-CoA:L-lysine N6-acetyltransferase
Process(es)
triglyceride biosynthetic process triglyceride catabolic process triglyceride acyl-chain remodeling acylglycerol acyl-chain remodeling lipid homeostasis lipid metabolic process metabolic process lipid catabolic process
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