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Proteintech
PNPLA6 Polyclonal Antibody
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Product Details
14261-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PNPLA6 Fusion Protein Ag5546 (977-1327 aa encoded by BC051768)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EERSASRTK QRAREWAKSM TSVLEPVLDL TYPVTSMFTG SAFNRSIHRV FQDKQIEDLW LPYFNVTTDI TASAMRVHKD GSLWRYVRAS MTLSGYLPPL CDPKDGHLLM DGGYINNLPA DIARSMGAKT VIAIDVGSQD ETDLSTYGDS LSGWWLLWKR LNPWADKVKV PDMAEIQSRL AYVSCVRQLE VVKSSSYCEY LRPPIDCFKT MDFGKFDQIY DVGYQYGKAV FGGWSRGNVI EKMLTDRRST DLNESRRADV LAFPSSGFTD LAEIVSRIEP PTSYVSDGCA DGEESDCLTE YEEDAGPDCS RDEGGSPEGA SPSTASEMEE EKSILRQRRC LPQEPPGSAT DA (977-1327 aa encoded by BC051768)
Target Information
This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CD73; Neuropathy target esterase; patatin-like phospholipase domain containing 6; Patatin-like phospholipase domain-containing protein 6; Swiss cheese; Swiss-cheese
Gene Aliases: AI661849; BNHS; iPLA2delta; LNMS; MSws; NTE; NTEMND; OMCS; PNPLA6; RGD1564611; SPG39; sws
UniProt ID: (Human) Q8IY17, (Mouse) Q3TRM4
Entrez Gene ID: (Human) 10908, (Mouse) 50767, (Rat) 360753
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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