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Invitrogen
PNPLA8 Polyclonal Antibody
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Product Details
PA5-32006
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human PNPLA8. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.84 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2549479
Product Specific Information
Recommended positive controls: Jurkat.
Predicted reactivity: Mouse (92%), Rabbit (94%), Chicken (84%), Rhesus Monkey (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Phospholipase A2 catalyzes cleavage of fatty acids from phospholipids, thereby regulating membrane physical properties and the release of lipid second messengers and growth factors. Phospholipase A2 activity also modulates cellular growth programs, inflammation, and ion channel function (Mancuso et al., 2000 [PubMed 10744668]).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Calcium-independent phospholipase A2-gamma; Intracellular membrane-associated calcium-independent phospholipase A2 gamma; iPLA2-2; iPLA2-gamma; membrane-associated calcium-independent phospholipase A2 gamma; patatin-like phospholipase domain containing 8; Patatin-like phospholipase domain-containing protein 8; PNPLA-gamma
Gene Aliases: BM-043; IPLA2-2; IPLA22; IPLA2G; iPLA2gamma; MMLA; PNPLA-gamma; PNPLA8
UniProt ID: (Human) Q9NP80
Entrez Gene ID: (Human) 50640
prostaglandin biosynthetic process
fatty acid metabolic process
cell death
arachidonic acid metabolic process
phosphatidylcholine catabolic process
phosphatidylcholine acyl-chain remodeling
phosphatidylethanolamine acyl-chain remodeling
linoleic acid metabolic process
phosphatidylethanolamine catabolic process
arachidonic acid secretion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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