Invitrogen

POMK Polyclonal Antibody

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Datasheet
Protocols
Questions & Answers
Datasheet
Protocols
Questions & Answers

Product Details

PA5-43488

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500
-
Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic peptide directed towards the N-terminal of human FLJ23356 (aa 74-123).
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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS with 2% sucrose

Contains

0.09% sodium azide

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2577295

Product Specific Information

Peptide sequence: CEELRTEVRQ LKRVGEGAVK RVFLSEWKEH KVALSQLTSL EMKDDFLHGL

Sequence homology: Cow: 93%; Dog: 86%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 93%

Target Information

This gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: POMK; probable inactive protein kinase-like protein SgK196; Protein kinase-like protein SgK196; Protein O-mannose kinase; Sugen kinase 196

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Gene Aliases: 4930444A02Rik; MDDGA12; MDDGC12; POMK; SGK196

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UniProt ID: (Human) Q9H5K3, (Mouse) Q3TUA9

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Entrez Gene ID: (Human) 84197, (Mouse) 74653

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Function(s)
protein kinase activity ATP binding phosphotransferase activity, alcohol group as acceptor carbohydrate kinase activity nucleotide binding phosphofructokinase activity phosphorylase kinase regulator activity cobinamide kinase activity phytol kinase activity kinase activity phosphatidylinositol phosphate kinase activity cyclin-dependent protein serine/threonine kinase regulator activity transferase activity transferase activity, transferring phosphorus-containing groups phenol kinase activity cyclin-dependent protein kinase activating kinase regulator activity inositol tetrakisphosphate 2-kinase activity heptose 7-phosphate kinase activity aminoglycoside phosphotransferase activity phosphatidylinositol 3-kinase activity eukaryotic elongation factor-2 kinase regulator activity eukaryotic elongation factor-2 kinase activator activity LPPG:FO 2-phospho-L-lactate transferase activity cytidine kinase activity glycerate 2-kinase activity (S)-lactate 2-kinase activity phosphoserine:homoserine phosphotransferase activity L-seryl-tRNA(Sec) kinase activity phosphocholine transferase activity polynucleotide 5'-hydroxyl-kinase activity ATP-dependent polynucleotide kinase activity GTP-dependent polynucleotide kinase activity farnesol kinase activity CTP:2-trans,-6-trans-farnesol kinase activity geraniol kinase activity geranylgeraniol kinase activity CTP:geranylgeraniol kinase activity prenol kinase activity 1-phosphatidylinositol-5-kinase activity 1-phosphatidylinositol-3-phosphate 4-kinase activity phosphatidylinositol-3,4-bisphosphate 5-kinase activity phosphatidylinositol bisphosphate kinase activity inositol-3,4,6-trisphosphate 1-kinase activity inositol 5-diphosphate pentakisphosphate 5-kinase activity inositol diphosphate tetrakisphosphate kinase activity
Process(es)
neuron migration protein phosphorylation protein O-linked glycosylation brain development learning or memory sensory perception of pain carbohydrate phosphorylation neuromuscular process phosphorylation
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