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Proteintech
POSH Polyclonal Antibody
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Product Details
14649-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Fruit fly,
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
POSH Fusion Protein Ag6243 (696-1056 aa encoded by BC053671)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VTMVSPSTA GGPAQKLQGN GVAGSPSVVP AAVVSAAHIQ TSPQAKVLLH MTGQMTVNQA RNAVRTVAAH NQERPTAAVT PIQVQNAAGL SPASVGLSHH SLASPQPAPL MPGSATHTAA ISISRASAPL ACAAAAPLTS PSITSASLEA EPSGRIVTVL PGLPTSPDSA SSACGNSSAT KPDKDSKKEK KGLLKLLSGA STKRKPRVSP PASPTLEVEL GSAELPLQGA VGPELPPGGG HGRAGSCPVD GDGPVTTAVA GAALAQDAFH RKASSLDSAV PIAPPPRQAC SSLGPVLNES RPVVCERHRV VVSYPPQSEA ELELKEGDIV FVHKKREDGW FKGTLQRNGK TGLFPGSFVE NI (696-1056 aa encoded by BC053671)
Target Information
This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase SH3RF1; FLJ21602; plenty of SH3 domains; Plenty of SH3s; Protein POSH; putative E3 ubiquitin-protein ligase SH3RF1; putative scaffolding protein POSH; RING finger protein 142; RING-type E3 ubiquitin transferase SH3RF1; SH3 domain-containing RING finger protein 1; SH3 multiple domains 2; SH3 multiple domains protein 2
Gene Aliases: 2200003J05Rik; KIAA1494; POSH; POSH1; R75531; RNF142; SH3MD2; SH3RF1
UniProt ID: (Human) Q7Z6J0, (Rat) Q71F54, (Mouse) Q69ZI1
Entrez Gene ID: (Human) 57630, (Rat) 306417, (Mouse) 59009
protein binding
zinc ion binding
ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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