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Invitrogen
POU3F2 Monoclonal Antibody (CL6228)
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FIGURE: 1 / 4
POU3F2 Antibody (MA5-35032) in ICC/IF
Immunofluorecent analysis of POU3F2 in U-251 cells using POU3F2 Monoclonal Antibody (CL6228) (Product # MA5-35032). Staining shows specific staining in the nucleoplasm in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).
Product Details
MA5-35032
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
CL6228
Immunogen
Recombinant Protein corresonding to Human POU3F2
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2848937
Product Specific Information
Immunogen sequence: ASNHYSLLTS SASIVHAEPP GGMQQGAGGY REAQSLVQGD YGALQSNGHP
Target Information
This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 7-Oct; Brain-2; brain-2 class III POU-domain protein; Brain-specific homeobox/POU domain protein 2; Nervous system-specific octamer-binding transcription factor N-Oct-3; Oct-7; Octamer-binding protein 7; Octamer-binding transcription factor 7; OTF-7; POU domain, class 3, transcription factor 2
Gene Aliases: 9430075J19Rik; A230098E07Rik; Brn-2; BRN2; N-Oct3; oct-7; OCT7; OTF-7; OTF7; POU3F2; POUF3
UniProt ID: (Human) P20265, (Mouse) P31360
Entrez Gene ID: (Human) 5454, (Mouse) 18992
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
RNA polymerase II transcription coactivator activity
transcription factor activity, sequence-specific DNA binding
protein binding
identical protein binding
DNA binding
sequence-specific DNA binding
HMG box domain binding
transcription from RNA polymerase II promoter
positive regulation of cell proliferation
epidermis development
negative regulation of gene expression
astrocyte development
cerebral cortex radially oriented cell migration
forebrain ventricular zone progenitor cell division
hypothalamus cell differentiation
neurohypophysis development
myelination in peripheral nervous system
neuron differentiation
positive regulation of multicellular organism growth
positive regulation of transcription from RNA polymerase II promoter
regulation of axonogenesis
cellular response to organic substance
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
Schwann cell development
regulation of cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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