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Invitrogen
PP1 alpha Polyclonal Antibody
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Product Details
PA5-17825
Product Specifications
Species Reactivity
Fruit fly,
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to the amino-terminal sequence of human PP1alpha
Conjugate
Form
Liquid
Concentration
92 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10986813
Product Specific Information
It is not recommended to aliquot this antibody.
This antibody is not cross-reactive with PP1-delta or PP1-gamma.
Target Information
This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CG6593-PA; CG6593-PB; GADD34; MGC15877; MGC1674; PP-1A; Pp1alpha-96A-PA; Pp1alpha-96A-PB; protein phosphatase 1; protein phosphatase 1, catalytic subunit, alpha isoform; protein phosphatase 1, catalytic subunit, alpha isozyme; protein phosphatase 1alpha at 96A; Protein phosphatase type 1 alpha, catalytic subunit; protein phosphatase-1d; serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit; Serine/threonine-protein phosphatase alpha-1 isoform; Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; testicular tissue protein Li 155
Gene Aliases: 96A; CG6593; dism2; Dmel\CG6593; Dmel_CG6593; DmPp1-96A; PP-1A; PP1; PP1 96A; PP1 alpha96a; Pp1-96A; PP1A; PP1alpha; Pp1alpha-96A; PP1alpha96A; PP1alpha[[1]]; PP1c; PP1c 96A; PPP1A; Ppp1c; PPP1CA
UniProt ID: (Human) P62136, (Fruit fly) P48461, (Mouse) P62137, (Rat) P62138
Entrez Gene ID: (Human) 5499, (Fruit fly) 42922, (Mouse) 19045, (Rat) 24668
glycogen metabolic process
regulation of glycogen biosynthetic process
regulation of glycogen catabolic process
protein dephosphorylation
cell cycle
dephosphorylation
lung development
negative regulation of protein binding
circadian regulation of gene expression
regulation of translational initiation by eIF2 alpha dephosphorylation
regulation of circadian rhythm
entrainment of circadian clock by photoperiod
branching morphogenesis of an epithelial tube
cell division
regulation of canonical Wnt signaling pathway
beta-catenin destruction complex disassembly
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
carbohydrate metabolic process
regulation of translation
female meiotic division
cellular process
rhythmic process
positive regulation of innate immune response
defense response to Gram-negative bacterium
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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