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Proteintech
PPAN Polyclonal Antibody
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Product Details
11006-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Xenopus
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PPAN Fusion Protein Ag1419 (174-473 aa encoded by BC009833)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is raised against the C-terminal of human PPAN and recognize bands around 55 kDa.
Immunogen sequence: LNTIKRCLL IDYNPDSQEL DFRHYSIKVV PVGASRGMKK LLQEKFPNMS RLQDISELLA TGAGLSESEA EPDGDHNITE LPQAVAGRGN MRAQQSAVRL TEIGPRMTLQ LIKVQEGVGE GKVMFHSFVS KTEEELQAIL EAKEKKLRLK AQRQAQQAQN VQRKQEQREA HRKKSLEGMK KARVGGSDEE ASGIPSRTAS LELGEDDDEQ EDDDIEYFCQ AVGEAPSEDL FPEAKQKRLA KSPGRKRKRW EMDRGRGRLC DQKFPKTKDK SQGAQARRGP RGASRDGGRG RGRGRPGKRV A (174-473 aa encoded by BC009833)
Target Information
The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Brix domain-containing protein 3; homolog of S. cerevisiae SSF1; Peter Pan homolog; second-step splicing factor 1; Ssf-1; suppressor of sterile four 1; Suppressor of SWI4 1 homolog
Gene Aliases: A230087P06Rik; BXDC3; PPAN; SSF; SSF-1; SSF1; SSF2
UniProt ID: (Human) Q9NQ55, (Mouse) Q91YU8
Entrez Gene ID: (Human) 56342, (Rat) 298699, (Mouse) 235036
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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