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Invitrogen
PPAN Polyclonal Antibody
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Product Details
PA5-60302
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PPAN. Recombinant protein control fragment (Product #RP-99100).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2645802
Product Specific Information
Immunogen sequence: RWEMDRGRGR LCDQKFPKTK DKSQGAQARR GPRGASRDGG
Highest antigen sequence identity to the following orthologs: Mouse - 38%, Rat - 38%.
Target Information
The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Brix domain-containing protein 3; homolog of S. cerevisiae SSF1; Peter Pan homolog; second-step splicing factor 1; Ssf-1; suppressor of sterile four 1; Suppressor of SWI4 1 homolog
Gene Aliases: BXDC3; PPAN; SSF; SSF-1; SSF1; SSF2
UniProt ID: (Human) Q9NQ55
Entrez Gene ID: (Human) 56342
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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