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Invitrogen
PPAPDC1A Polyclonal Antibody
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Product Details
PA5-20864
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A 14 amino acid peptide near the carboxy terminus of human PPAPDC1A.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11157635
Product Specific Information
A suggested positive control is human brain tissue lysate.
PA5-20864 can be used with blocking peptide PEP-0978.
Target Information
Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide(NEM) and Mg2+. A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated. PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity. PPAPDC1A is preferentially expressed in endothelial cells. Studies of PPAPDC1A and PAP activity suggest that they may play a role in angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: diacylglycerol pyrophosphate like 2; diacylglycerol pyrophosphate phosphatase-like 2; phosphatidate phosphatase PPAPDC1A; phosphatidic acid phosphatase type 2 domain containing 1A; Phosphatidic acid phosphatase type 2 domain-containing protein 1A; Phospholipid phosphatase 4; RP11-257O17.1
Gene Aliases: C030048B12Rik; DPPL2; Gm1090; PLPP4; PPAPDC1; PPAPDC1A; RGD1306289
UniProt ID: (Human) Q5VZY2, (Mouse) Q0VBU9
Entrez Gene ID: (Human) 196051, (Rat) 309014, (Mouse) 381925
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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