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Proteintech
PPFIBP2 Polyclonal Antibody
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Product Details
13953-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PPFIBP2 Fusion Protein Ag5064 (577-876 aa encoded by BC021714)
Conjugate
Form
Liquid
Concentration
0.31 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: IFARQWVSS GHTLLTATPQ DMEKELGIKH PLHRKKLVLA VKAINTKQEE KSALLDHIWV TRWLDDIGLP QYKDQFHESR VDGRMLQYLT VNDLLFLKVT SQLHHLSIKC AIHVLHVNKF NPHCLHRRPA DESNLSPSEV VQWSNHRVME WLRSVDLAEY APNLRGSGVH GGLIILEPRF TGDTLAMLLN IPPQKTLLRR HLTTKFNALI GPEAEQEKRE KMASPAYTPL TTTAKVRPRK LGFSHFGNIR KKKFDESTDY ICPMEPSDGV SDSHRVYSGY RGLSPLDAPE LDGLDQVGQI S (577-876 aa encoded by BC021714)
Target Information
The PPFIBP2 (PPFIA Binding Protein 2) gene encodes a protein that belongs to the liprin family, which is involved in intracellular signaling and cytoskeletal organization. Located on chromosome 1, PPFIBP2 is primarily known for its role in synaptic function and cell adhesion. The protein interacts with receptor protein tyrosine phosphatases, particularly PTPRF and PTPRD, and plays a critical role in the formation and maintenance of synaptic contacts. PPFIBP2 facilitates the proper localization of synaptic vesicles and synapse-specific proteins, contributing to synaptic stability and plasticity. Disruption of PPFIBP2 expression or function has been linked to neurological disorders, emphasizing its importance in neural communication. Additionally, PPFIBP2 has been implicated in cancer, where it may influence tumor cell adhesion and migration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Coiled-coil-like protein 1; liprin beta 2; Liprin-beta-2; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 2; protein tyrosine phosphatase, receptor-type, F interacting protein, binding protein 2; PTPRF interacting protein, binding protein 2 (liprin beta 2); PTPRF-interacting protein-binding protein 2
Gene Aliases: Cclp1; PPFIBP2
UniProt ID: (Human) Q8ND30, (Mouse) O35711
Entrez Gene ID: (Human) 8495, (Mouse) 19024, (Rat) 308918
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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