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Immunogen sequence: MENVESDPKT DRPKEEIRID ATTVFVDPYE EADAQIAQER KTQLKVAPET KVKSSQPQAG SQGPQTFRQG VGKYINPAAT KRAAEEEPST SATVPMSKKK PSRGFGDFSS
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 82%.
This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. This protein interacts with the proteinase inhibitor eglin c and is localized in the nucleus. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CYC4; cyclophilin, 60kDa; Cyclophilin-60; Cyclophilin-like protein Cyp-60; peptidylprolyl cis-trans isomerase; peptidylprolyl isomerase (cyclophilin)-like 2; PPIase; Probable inactive peptidyl-prolyl cis-trans isomerase-like 2; RING-type E3 ubiquitin-protein ligase PPIL2; Rotamase PPIL2; U-box domain containing 7
Gene Aliases: CYC4; Cyp-60; CYP60; hCyP-60; PPIL2; UBOX7
UniProt ID: (Human) Q13356
Entrez Gene ID: (Human) 23759
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