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Proteintech
PPM2C Polyclonal Antibody
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Product Details
21176-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PPM2C Fusion Protein Ag15453 (1-154 aa encoded by BC047619)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MPAPTQLFF PLIRNCELSR IYGTACYCHH KHLCCSSSYI PQSRLRYTPH PAYATFCRPK ENWWQYTQGR RYASTPQKFY LTPPQVNSIL KANEYSFKVP EFDGKNVSSI LGFDSNQLPA NAPIEDRRSA ATCLQTRGML LGVFDGHAGC ACSQA (1-154 aa encoded by BC047619)
Target Information
PDP1 is a Pyruvate dehydrogenase and helps catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial; FLJ32517; FLJ56179; MGC119646; PDP 1; PDPC 1; Protein phosphatase 2C; protein phosphatase 2C, magnesium dependent, catalytic subunit; protein phosphatase 2C, magnesium-dependent, catalytic subunit; protein phosphatase, Mg2+/Mn2+ dependent 2A; pyruvate dehydrogenase; pyruvate dehydrogenase (Lipoamide) phosphatase-phosphatase; Pyruvate dehydrogenase phosphatase catalytic subunit 1; pyruvate dehydrogenase phosphatase isoenzyme 2
Gene Aliases: Gm1024; PDH; PDP; PDP1; PDPC; PPM2A; PPM2C
UniProt ID: (Human) Q9P0J1, (Mouse) Q3UV70
Entrez Gene ID: (Human) 54704, (Mouse) 381511
magnesium ion binding
protein serine/threonine phosphatase activity
magnesium-dependent protein serine/threonine phosphatase activity
[pyruvate dehydrogenase (lipoamide)] phosphatase activity
calcium ion binding
protein binding
protein complex binding
catalytic activity
phosphoprotein phosphatase activity
hydrolase activity
metal ion binding
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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