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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • PPP1R12B Antibodies

          Proteintech

          PPP1R12B Polyclonal Antibody

          3 References
          View all (7) PPP1R12B antibodies

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          Datasheet
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          Cite PPP1R12B Polyclonal Antibody

          • Antibody Testing Data (5)
          PPP1R12B Antibody in Immunocytochemistry (ICC/IF)
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          PPP1R12B Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          PPP1R12B Antibody (13366-1-AP) in ICC/IF

          Immunofluorescent analysis of (-20°C Ethanol) fixed NIH/3T3 cells using (Product # 13366-1-AP) (PPP1R12B antibody) at dilution of 1:100 and CoraLite488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PPP1R12B Antibody in Immunocytochemistry (ICC/IF)
          PPP1R12B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PPP1R12B Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PPP1R12B Antibody in Western Blot (WB)
          PPP1R12B Antibody in Western Blot (WB)

          Product Details

          13366-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:3,200
          View 2 publications 2 publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200
          -

          Immunocytochemistry (ICC/IF)

          1:100
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          PPP1R12B Fusion Protein Ag4185 (1-386 aa encoded by BC034430)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.13 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MAELEHLGG KRAESARMRR AEQLRRWRGS LTEQEPAERR GAGRQPLTRR GSPRVRFEDG AVFLAACSSG DTDEVRKLLA RGADINTVNV DGLTALHQAC IDENLDMVKF LVENRANVNQ QDNEGWTPLH AAASCGYLNI AEYFINHGAS VGIVNSEGEV PSDLAEEPAM KDLLLEQVKK QGVDLEQSRK EEEQQMLQDA RQWLNSGKIE DVRQARSGAT ALHVAAAKGY SEVLRLLIQA GYELNVQDYD GWTPLHAAAH WGVKEACSIL AEALCDMDIR NKLGQTPFDV ADEGLVEHLE LLQKKQNVLR SEKETRNKLI ESDLNSKIQS GFFKNKEKML YEEETPKSQE MEEENKESSS SSSEEEEGED EASESETEKE AVLFWPF (1-386 aa encoded by BC034430)

          Target Information

          Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Myosin phosphatase target subunit 2; myosin phosphatase, target subunit 2; Myosin phosphatase-targeting subunit 2; Protein phosphatase 1 regulatory subunit 12B; protein phosphatase 1, regulatory (inhibitor) subunit 12B; protein phosphatase 1, regulatory subunit 12B

          View more View less

          Gene Aliases: 1810037O03Rik; 9530009M10Rik; AI132431; MYPT2; PP1bp55; PPP1R12B

          View more View less

          UniProt ID: (Human) O60237

          View more View less

          Entrez Gene ID: (Human) 4660, (Mouse) 329251, (Rat) 304813

          View more View less

          Function(s)
          protein binding enzyme activator activity phosphatase regulator activity protein kinase binding molecular_function
          Process(es)
          signal transduction biological_process G2/M transition of mitotic cell cycle regulation of muscle contraction positive regulation of catalytic activity
          It has to be done as per old AB suggested Products section.
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