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Invitrogen
PPP1R15B Polyclonal Antibody
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PPP1R15B Antibody (PA5-106285) in IHC (P)
Immunohistochemistry analysis of PPP1R15B in human normal tissues adjacent to liver cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with PPP1R15B polyclonal antibody (Product # PA5-106285) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-106285
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PPP1R15B(Accession Q5SWA1), corresponding to amino acid residues H633-I683.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2853962
Product Specific Information
Antibody detects endogenous levels of total PPP1R15B.
Target Information
Maintains low levels of EIF2S1 phosphorylation in unstressed cells by promoting its dephosphorylation by PP1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Constitutive repressor of eIF2alpha phosphorylation; CReP; Protein phosphatase 1 regulatory subunit 15B; protein phosphatase 1, regulatory (inhibitor) subunit 15B
Gene Aliases: 1810033K10Rik; AI606441; C530022L24Rik; CREP; MSSGM2; PPP1R15B
UniProt ID: (Human) Q5SWA1, (Mouse) Q8BFW3
Entrez Gene ID: (Human) 84919, (Rat) 304799, (Mouse) 108954
response to oxidative stress
ER overload response
dephosphorylation
response to endoplasmic reticulum stress
response to hydrogen peroxide
regulation of translation
regulation of translational initiation
peptidyl-serine dephosphorylation
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
negative regulation of protein phosphorylation
negative regulation of PERK-mediated unfolded protein response
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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