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Invitrogen
PPP2R5B Polyclonal Antibody
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Product Details
PA5-85443
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human PPP2R5B. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.92 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2792583
Product Specific Information
Keep as concentrated solution.
Predicted reactivity: Mouse (99%), Rat (100%), Rabbit (100%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. Two transcript variants encoding the same protein have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FLJ35411; PP2A; PP2A B subunit isoform B'-beta; PP2A B subunit isoform B56-beta; PP2A B subunit isoform PR61-beta; PP2A B subunit isoform R5-beta; protein phosphatase 2 regulatory subunit B', beta; protein phosphatase 2, regulatory subunit B', beta isoform; serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, beta isoform; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
Gene Aliases: B56B; PPP2R5B; PR61B
UniProt ID: (Human) Q15173
Entrez Gene ID: (Human) 5526
regulation of receptor activity
positive regulation of neuron projection development
regulation of phosphatidylinositol 3-kinase signaling
positive regulation of protein complex assembly
regulation of protein autophosphorylation
regulation of protein phosphatase type 2A activity
IRE1-mediated unfolded protein response
positive regulation of transcription from RNA polymerase II promoter
regulation of peptidyl-tyrosine phosphorylation
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of neurotrophin TRK receptor signaling pathway
negative regulation of G0 to G1 transition
positive regulation of cell cycle arrest
cellular response to growth factor stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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