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Invitrogen
PPP2R5C Polyclonal Antibody
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FIGURE: 1 / 7
PPP2R5C Antibody (PA5-115789) in ICC/IF
Immunocytochemistry analysis of PPP2R5C in A549 cells. Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody (Product # PA5-115789). Secondary staining was applied with mouse anti-beta tubulin (1 hr at 37°, AlexaFluor 594 conjugated goat anti-rabbit IgG (Red), AlexaFluor 488 conjugated goat anti-mouse IgG (Green) and DAPI.
Product Details
PA5-115789
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PPP2R5C(Accession Q13362), corresponding to amino acid residues M452-D502.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2900424
Product Specific Information
Antibody detects endogenous levels of total PPP2R5C.
Target Information
Phosphatases are involved in the regulation of MAP kinases.Protein phosphatase 2A (PP2A) is a critical component of the pathway responsible for p38 MAPK up-regulation of SERT catalytic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: B' alpha regulatory subunit; B55-GAMMA; IMYPNO; IMYPNO1; MGC23064; MGC33570; PP2A B subunit isoform B'-gamma; PP2A B subunit isoform B56-gamma; PP2A B subunit isoform PR61-gamma; PP2A B subunit isoform R5-gamma; PR52; PR55G; protein phosphatase 2 regulatory subunit B', gamma; protein phosphatase 2, regulatory subunit B (B56), gamma isoform; protein phosphatase 2, regulatory subunit B', gamma isoform; Renal carcinoma antigen NY-REN-29; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform
Gene Aliases: B56G; KIAA0044; PPP2R5C; PR61G
UniProt ID: (Human) Q13362
Entrez Gene ID: (Human) 5527, (Rat) 691318
proteolysis
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
negative regulation of cell proliferation
protein processing
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
proteasome-mediated ubiquitin-dependent protein catabolic process
regulation of catalytic activity
signal transduction
regulation of phosphatidylinositol 3-kinase signaling
regulation of protein phosphatase type 2A activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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