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Proteintech
PPP3R2 Polyclonal Antibody
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Product Details
14005-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PPP3R2 Fusion Protein Ag5097 (1-173 aa encoded by BC030595)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MSTMGNEAS YPAEMCSHFD NDEIKRLGRR FKKLDLDKSG SLSVEEFMSL PELRHNPLVR RVIDVFDTDG DGEVDFKEFI LGTSQFSVKG DEEQKLRFAF SIYDMDKDGY ISNGELFQVL KMMVGNNLTD WQLQQLVDKT IIILDKDGDG KISFEEFSAV VRDLEIHKKL VLIV (1-173 aa encoded by BC030595)
Target Information
This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: calcineurin B subunit; calcineurin B, type II (19kDa); Calcineurin B-like protein; Calcineurin BII; Calcineurin subunit B type 2; CBLP; CNBII; PP2B beta 2; PPP3R1-like; protein phospatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II); Protein phosphatase 2B regulatory subunit 2; protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), beta isoform (calcineurin B, type II); protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, beta isoform (calcineurin B, type II); protein phosphatase 3 (formerly 2B), regulatory subunit B, beta isoform; Protein phosphatase 3 regulatory subunit B beta isoform; protein phosphatase 3, regulatory subunit B, beta; ty
Gene Aliases: CaNB2; CBLP; CnB2; PPP3R2; PPP3RL
UniProt ID: (Human) Q96LZ3, (Mouse) Q63811
Entrez Gene ID: (Human) 5535, (Mouse) 19059
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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