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Immunogen sequence: SKAQLSQTVQ SRLVSCKILG KLTNKFDAHT IKREILPLVK SLCQDVEYEV RSCMCRQLEN IAQGIGTELT KSVVLPELIE LSRDEGSSVR LAAFET
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 96%.
The protein encoded by this gene is a HEAT-like repeat-containing protein. The HEAT repeat is a tandemly repeated, 37-47 amino acid long module occurring in a number of cytoplasmic proteins. Arrays of HEAT repeats form a rod-like helical structure and appear to function as protein-protein interaction surfaces. The repeat-containing region of this protein has some similarity to the constant regulatory domain of the protein phosphatase 2A PR65/A subunit. The function of this particular gene product has not been determined. Alternative splicing has been observed for this gene and two transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cilia and flagella associated protein 14; HEAT-like repeat-containing protein; protein phosphatase 4, regulatory subunit 4; Serine/threonine-protein phosphatase 4 regulatory subunit 4
Gene Aliases: CFAP14; KIAA1622; PP4R4; PPP4R4
UniProt ID: (Human) Q6NUP7
Entrez Gene ID: (Human) 57718
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