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PPY Antibody (PA5-115719) in IHC (P)
Immunohistochemistry analysis of PPY in human pancreatic cancer and adjacent normal tissues. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115719) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Product Details
PA5-115719
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human PPY(Accession P01298), corresponding to amino acid residues A41-S91.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2900354
Product Specific Information
Antibody detects endogenous levels of total Pancreatic Polypeptide.
Target Information
Pancreatic polypeptide (PP) is a 36 amino-acid residue peptide with sequence and 3-D structural homology with NPY and PYY. PP is the least conserved of the three peptides and was the first to be identified. It is almost exclusively expressed in the endocrine pancreas and released in response to cholinergic stimulation and food intake. PP has inhibitory effects on gall bladder secretion, intestinal motility and pancreatic secretion. PP may serve as a marker for certain gut endocrine tumors including carcinoid tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HGNC:9327; IOPPP; Pancreatic polypeptide prohormone; Pancreatic polypeptide Y; pancreatic prohormone; PH; PP; PP1; PPA1; PPase; prepro-PP (prepropancreatic polypeptide); SID6-8061
Gene Aliases: AV061413; IGSPP; PNP; PP; PPY
UniProt ID: (Human) P01298, (Rat) P06303, (Mouse) P10601
Entrez Gene ID: (Human) 5539, (Rat) 24677, (Mouse) 19064
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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