Proteintech

PQBP1 Polyclonal Antibody

PQBP1 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 8

PQBP1 Antibody (16264-1-AP) in ICC/IF

Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 16264-1-AP (PQBP1 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

PQBP1 Antibody in Immunoprecipitation (IP)

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Product Details

16264-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 2 publications 2 publications

Immunohistochemistry (IHC)

Assay-dependent

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

1:50-1:500

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

PQBP1 Fusion Protein Ag9329 (1-265 aa encoded by BC012358)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.22 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MPLPVALQT RLAKRGILKH LEPEPEEEII AEDYDDDPVD YEATRLEGLP PSWYKVFDPS CGLPYYWNAD TDLVSWLSPH DPNSVVTKSA KKLRSSNADA EEKLDRSHDK SDRGHDKSDR SHEKLDRGHD KSDRGHDKSD RDRERGYDKV DRERERDRER DRDRGYDKAD REEGKERRHH RREELAPYPK SKKAVSRKDE ELDPMDPSSY SDAPRGTWST GLPKRNEAKT GADTTAAGPL FQQRPYPSPG AVLRANAEAS RTKQQD (1-265 aa encoded by B C012358)

Target Information

PQBP1 is a nuclear polyglutamine-binding protein that contains a WW domain. Mutations in this gene are associated with X-linked mental retardation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTD by suppressing eEF2 phosphorylation.

Molecular cell

Shen Y,Zhang ZC,Cheng S,Liu A,Zuo J,Xia S,Liu X,Liu W,Jia Z,Xie W,Han J

Thu Apr 01 00:00:00 UTC 2021

PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTD by suppressing eEF2 phosphorylation.

Molecular cell

Shen Y,Zhang ZC,Cheng S,Liu A,Zuo J,Xia S,Liu X,Liu W,Jia Z,Xie W,Han J

Thu Apr 01 00:00:00 UTC 2021

PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTD by suppressing eEF2 phosphorylation.

Molecular cell

Shen Y,Zhang ZC,Cheng S,Liu A,Zuo J,Xia S,Liu X,Liu W,Jia Z,Xie W,Han J

Thu Apr 01 00:00:00 UTC 2021

Barrier-to-Autointegration Factor 1 Protects against a Basal cGAS-STING Response.

mBio

Ma H,Qian W,Bambouskova M,Collins PL,Porter SI,Byrum AK,Zhang R,Artyomov M,Oltz EM,Mosammaparast N,Miner JJ,Diamond MS

Tue Mar 10 00:00:00 UTC 2020

Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.

Acta neuropathologica

Neumann M,Valori CF,Ansorge O,Kretzschmar HA,Munoz DG,Kusaka H,Yokota O,Ishihara K,Ang LC,Bilbao JM,Mackenzie IR

Thu Nov 01 00:00:00 UTC 2012

Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.

Acta neuropathologica

Neumann M,Valori CF,Ansorge O,Kretzschmar HA,Munoz DG,Kusaka H,Yokota O,Ishihara K,Ang LC,Bilbao JM,Mackenzie IR

Thu Nov 01 00:00:00 UTC 2012

Bioinformatics

Protein Aliases: 38 kDa nuclear protein containing a WW domain; Npw38; Polyglutamine tract-binding protein 1; Polyglutamine-binding protein 1; PQBP-1; scurfy candidate 2

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Gene Aliases: JM26; MRX2; MRX55; MRXS3; MRXS8; NPW38; PQBP-1; PQBP1; RENS1; Sfc2; SHS

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UniProt ID: (Human) O60828, (Rat) Q6PCT5, (Mouse) Q91VJ5

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Entrez Gene ID: (Human) 10084, (Rat) 302557, (Mouse) 54633

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Function(s)

DNA binding transcription coactivator activity protein binding protein C-terminus binding ribonucleoprotein complex binding

Process(es)

alternative mRNA splicing, via spliceosome transcription, DNA-templated regulation of transcription, DNA-templated neuron projection development stress granule assembly regulation of RNA splicing regulation of dendrite morphogenesis cilium morphogenesis mRNA processing RNA splicing

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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PQBP1 Polyclonal Antibody

PQBP1 Antibody (16264-1-AP) in ICC/IF

Product Details

16264-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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